Class: ReceptorComposite

URI: ak_schema:ReceptorComposite

classDiagram class ReceptorComposite click ReceptorComposite href "../ReceptorComposite" AlphaBetaTCR <|-- ReceptorComposite click AlphaBetaTCR href "../AlphaBetaTCR" GammaDeltaTCR <|-- ReceptorComposite click GammaDeltaTCR href "../GammaDeltaTCR" BCellReceptor <|-- ReceptorComposite click BCellReceptor href "../BCellReceptor" AKObject <|-- ReceptorComposite click AKObject href "../AKObject" ReceptorComposite <|-- PairedReceptorComposite click PairedReceptorComposite href "../PairedReceptorComposite" ReceptorComposite : akc_id ReceptorComposite : antibody_complex ReceptorComposite --> "0..1" AntibodyAntigenComplex : antibody_complex click AntibodyAntigenComplex href "../AntibodyAntigenComplex" ReceptorComposite : antigen ReceptorComposite --> "0..1" Antigen : antigen click Antigen href "../Antigen" ReceptorComposite : epitope ReceptorComposite --> "0..1" Epitope : epitope click Epitope href "../Epitope" ReceptorComposite : igh_chain ReceptorComposite : igk_chain ReceptorComposite : igl_chain ReceptorComposite : mhc ReceptorComposite --> "0..1" MajorHistocompatibilityComplex : mhc click MajorHistocompatibilityComplex href "../MajorHistocompatibilityComplex" ReceptorComposite : paired_chain ReceptorComposite : species ReceptorComposite --> "0..1" SpeciesOntology : species click SpeciesOntology href "../SpeciesOntology" ReceptorComposite : tcr_complex ReceptorComposite --> "0..1" TCRpMHCComplex : tcr_complex click TCRpMHCComplex href "../TCRpMHCComplex" ReceptorComposite : tra_chain ReceptorComposite : trb_chain ReceptorComposite : trd_chain ReceptorComposite : trg_chain

Inheritance

AKObject
- ReceptorComposite [ AlphaBetaTCR GammaDeltaTCR BCellReceptor]
  - PairedReceptorComposite

Slots

Name	Cardinality and Range	Description	Inheritance
species	0..1 SpeciesOntology	Binomial designation of subject's species	direct
tcr_complex	0..1 TCRpMHCComplex	TCR complex	direct
antibody_complex	0..1 AntibodyAntigenComplex	Antibody antigen complex	direct
antigen	0..1 Antigen	A material entity with antigen role	direct
epitope	0..1 Epitope	Epitope of an antigen, which can be recognized by a T cell receptor or antibo...	direct
mhc	0..1 MajorHistocompatibilityComplex	Major histocompatibility complex	direct
tra_chain	0..1 Uriorcurie	T cell receptor alpha chain	AlphaBetaTCR
trb_chain	0..1 Uriorcurie	T cell receptor beta chain	AlphaBetaTCR
trg_chain	0..1 Uriorcurie	T cell receptor gamma chain	GammaDeltaTCR
trd_chain	0..1 Uriorcurie	T cell receptor delta chain	GammaDeltaTCR
igh_chain	0..1 Uriorcurie	IG heavy chain	BCellReceptor
igk_chain	0..1 Uriorcurie	IG kappa light chain	BCellReceptor
igl_chain	0..1 Uriorcurie	IG lambda light chain	BCellReceptor
akc_id	1 Uriorcurie	A unique identifier for a thing in the AKC	AKObject
paired_chain	0..1 Boolean	Flag to indicate the receptor object has both chains defined	ImmuneReceptor

Usages

used by	used in	type	used
AIRRKnowledgeCommons	receptor_composites	range	ReceptorComposite
AIRRSequencingAssay	receptor_composites	range	ReceptorComposite
TCellReceptorEpitopeBindingAssay	receptor_composites	range	ReceptorComposite
AntibodyAntigenBindingAssay	receptor_composites	range	ReceptorComposite

Identifier and Mapping Information

Schema Source

from schema: https://github.com/airr-knowledge/ak-schema

Mappings

Mapping Type	Mapped Value
self	ak_schema:ReceptorComposite
native	ak_schema:ReceptorComposite

LinkML Source

Direct

name: ReceptorComposite
from_schema: https://github.com/airr-knowledge/ak-schema
is_a: AKObject
mixins:
- AlphaBetaTCR
- GammaDeltaTCR
- BCellReceptor
slots:
- species
- tcr_complex
- antibody_complex
- antigen
- epitope
- mhc

Induced

name: ReceptorComposite
from_schema: https://github.com/airr-knowledge/ak-schema
is_a: AKObject
mixins:
- AlphaBetaTCR
- GammaDeltaTCR
- BCellReceptor
attributes:
  species:
    name: species
    annotations:
      nullable:
        tag: nullable
        value: false
    description: Binomial designation of subject's species
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: species
    owner: ReceptorComposite
    domain_of:
    - Participant
    - Chain
    - ImmuneReceptor
    - AntibodyAntigenComplex
    - TCRpMHCComplex
    - ReceptorComposite
    - AlphaBetaReceptorComposite
    - GammaDeltaReceptorComposite
    - BCellReceptorComposite
    - AlleleDescription
    - GermlineSet
    - Subject
    range: SpeciesOntology
  tcr_complex:
    name: tcr_complex
    description: TCR complex
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: tcr_complex
    owner: ReceptorComposite
    domain_of:
    - ReceptorComposite
    - AlphaBetaReceptorComposite
    - GammaDeltaReceptorComposite
    range: TCRpMHCComplex
  antibody_complex:
    name: antibody_complex
    description: Antibody antigen complex
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: antibody_complex
    owner: ReceptorComposite
    domain_of:
    - ReceptorComposite
    - BCellReceptorComposite
    range: AntibodyAntigenComplex
  antigen:
    name: antigen
    description: A material entity with antigen role
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: antigen
    owner: ReceptorComposite
    domain_of:
    - AntibodyAntigenComplex
    - TCRpMHCComplex
    - ReceptorComposite
    - AlphaBetaReceptorComposite
    - GammaDeltaReceptorComposite
    - BCellReceptorComposite
    - ReceptorReactivity
    - QueryTCR
    - QueryIG
    range: Antigen
  epitope:
    name: epitope
    description: Epitope of an antigen, which can be recognized by a T cell receptor
      or antibody
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: epitope
    owner: ReceptorComposite
    domain_of:
    - AntibodyAntigenComplex
    - TCRpMHCComplex
    - ReceptorComposite
    - AlphaBetaReceptorComposite
    - GammaDeltaReceptorComposite
    - BCellReceptorComposite
    - QueryTCR
    range: Epitope
  mhc:
    name: mhc
    description: Major histocompatibility complex
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: mhc
    owner: ReceptorComposite
    domain_of:
    - TCRpMHCComplex
    - ReceptorComposite
    - AlphaBetaReceptorComposite
    - GammaDeltaReceptorComposite
    - BCellReceptorComposite
    - QueryTCR
    range: MajorHistocompatibilityComplex
  tra_chain:
    name: tra_chain
    description: T cell receptor alpha chain
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: tra_chain
    owner: ReceptorComposite
    domain_of:
    - AlphaBetaTCR
    - QueryAlphaBetaTCR
    range: uriorcurie
  trb_chain:
    name: trb_chain
    description: T cell receptor beta chain
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: trb_chain
    owner: ReceptorComposite
    domain_of:
    - AlphaBetaTCR
    - QueryAlphaBetaTCR
    range: uriorcurie
  trg_chain:
    name: trg_chain
    description: T cell receptor gamma chain
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: trg_chain
    owner: ReceptorComposite
    domain_of:
    - GammaDeltaTCR
    range: uriorcurie
  trd_chain:
    name: trd_chain
    description: T cell receptor delta chain
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: trd_chain
    owner: ReceptorComposite
    domain_of:
    - GammaDeltaTCR
    range: uriorcurie
  igh_chain:
    name: igh_chain
    description: IG heavy chain
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: igh_chain
    owner: ReceptorComposite
    domain_of:
    - BCellReceptor
    range: uriorcurie
  igk_chain:
    name: igk_chain
    description: IG kappa light chain
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: igk_chain
    owner: ReceptorComposite
    domain_of:
    - BCellReceptor
    range: uriorcurie
  igl_chain:
    name: igl_chain
    description: IG lambda light chain
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: igl_chain
    owner: ReceptorComposite
    domain_of:
    - BCellReceptor
    range: uriorcurie
  akc_id:
    name: akc_id
    description: A unique identifier for a thing in the AKC.
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    slot_uri: schema:identifier
    identifier: true
    alias: akc_id
    owner: ReceptorComposite
    domain_of:
    - AKObject
    range: uriorcurie
    required: true
  paired_chain:
    name: paired_chain
    description: Flag to indicate the receptor object has both chains defined
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: paired_chain
    owner: ReceptorComposite
    domain_of:
    - ImmuneReceptor
    range: boolean