To be considered complete, the procedure used for library construction MUST generate sequences that 1) include the first V gene codon that encodes the mature polypeptide chain (i.e. after the leader sequence) and 2) include the last complete codon of the J gene (i.e. 1 bp 5' of the J->C splice site) and 3) provide sequence information for all positions between 1) and 2). To be considered complete & untemplated, the sections of the sequences defined in points 1) to 3) of the previous sentence MUST be untemplated, i.e. MUST NOT overlap with the primers used in library preparation. mixed should only be used if the procedure used for library construction will likely produce multiple categories of sequences in the given experiment. It SHOULD NOT be used as a replacement of a NULL value.
from schema: https://github.com/airr-knowledge/ak-schema
Mappings
Mapping Type
Mapped Value
self
ak_schema:complete_sequences
native
ak_schema:complete_sequences
LinkML Source
name: complete_sequences
annotations:
nullable:
tag: nullable
value: false
description: To be considered `complete`, the procedure used for library construction
MUST generate sequences that 1) include the first V gene codon that encodes the
mature polypeptide chain (i.e. after the leader sequence) and 2) include the last
complete codon of the J gene (i.e. 1 bp 5' of the J->C splice site) and 3) provide
sequence information for all positions between 1) and 2). To be considered `complete
& untemplated`, the sections of the sequences defined in points 1) to 3) of the
previous sentence MUST be untemplated, i.e. MUST NOT overlap with the primers used
in library preparation. `mixed` should only be used if the procedure used for library
construction will likely produce multiple categories of sequences in the given experiment.
It SHOULD NOT be used as a replacement of a NULL value.
from_schema: https://github.com/airr-knowledge/ak-schema
rank: 1000
alias: complete_sequences
domain_of:
- NucleicAcidProcessing
- SampleProcessing
range: CompleteSequencesEnum