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Class: ReceptorReactivity

URI: ak_schema:ReceptorReactivity

classDiagram class ReceptorReactivity click ReceptorReactivity href "../ReceptorReactivity" AIRRStandards <|-- ReceptorReactivity click AIRRStandards href "../AIRRStandards" ReceptorReactivity : antigen ReceptorReactivity --> "0..1" AntigenOntology : antigen click AntigenOntology href "../AntigenOntology" ReceptorReactivity : antigen_source_species ReceptorReactivity --> "0..1" AntigenSourceSpeciesOntology : antigen_source_species click AntigenSourceSpeciesOntology href "../AntigenSourceSpeciesOntology" ReceptorReactivity : antigen_type ReceptorReactivity --> "0..1" AntigenTypeEnum : antigen_type click AntigenTypeEnum href "../AntigenTypeEnum" ReceptorReactivity : ligand_type ReceptorReactivity --> "0..1" LigandTypeEnum : ligand_type click LigandTypeEnum href "../LigandTypeEnum" ReceptorReactivity : mhc_allele_1 ReceptorReactivity : mhc_allele_2 ReceptorReactivity : mhc_class ReceptorReactivity --> "0..1" MhcClassEnum : mhc_class click MhcClassEnum href "../MhcClassEnum" ReceptorReactivity : mhc_gene_1 ReceptorReactivity --> "0..1" MhcGene1Ontology : mhc_gene_1 click MhcGene1Ontology href "../MhcGene1Ontology" ReceptorReactivity : mhc_gene_2 ReceptorReactivity --> "0..1" MhcGene2Ontology : mhc_gene_2 click MhcGene2Ontology href "../MhcGene2Ontology" ReceptorReactivity : peptide_end ReceptorReactivity : peptide_start ReceptorReactivity : reactivity_method ReceptorReactivity --> "0..1" ReactivityMethodEnum : reactivity_method click ReactivityMethodEnum href "../ReactivityMethodEnum" ReceptorReactivity : reactivity_readout ReceptorReactivity --> "0..1" ReactivityReadoutEnum : reactivity_readout click ReactivityReadoutEnum href "../ReactivityReadoutEnum" ReceptorReactivity : reactivity_unit ReceptorReactivity : reactivity_value

Inheritance

Slots

Name Cardinality and Range Description Inheritance
ligand_type 0..1
LigandTypeEnum		 Classification of ligand binding to receptor direct
antigen_type 0..1
AntigenTypeEnum		 The type of antigen before processing by the immune system direct
antigen 0..1
AntigenOntology		 The substance against which the receptor was tested direct
antigen_source_species 0..1
AntigenSourceSpeciesOntology		 The species from which the antigen was isolated direct
peptide_start 0..1
Integer		 Start position of the peptide within the reference protein sequence direct
peptide_end 0..1
Integer		 End position of the peptide within the reference protein sequence direct
mhc_class 0..1
MhcClassEnum		 direct
mhc_gene_1 0..1
MhcGene1Ontology		 The MHC gene to which the mhc_allele_1 belongs direct
mhc_allele_1 0..1
String		 Allele designation of the MHC alpha chain direct
mhc_gene_2 0..1
MhcGene2Ontology		 The MHC gene to which the mhc_allele_2 belongs direct
mhc_allele_2 0..1
String		 Allele designation of the MHC class II beta chain or the invariant beta2-micr... direct
reactivity_method 0..1
ReactivityMethodEnum		 The methodology used to assess expression (assay implemented in experiment) direct
reactivity_readout 0..1
ReactivityReadoutEnum		 Reactivity measurement read-out direct
reactivity_value 0..1
Float		 The absolute (processed) value of the measurement direct
reactivity_unit 0..1
String		 The unit of the measurement direct

Usages

used by used in type used
Receptor reactivity_measurements range ReceptorReactivity

Identifier and Mapping Information

Schema Source

  • from schema: https://github.com/airr-knowledge/ak-schema

Mappings

Mapping Type Mapped Value
self ak_schema:ReceptorReactivity
native ak_schema:ReceptorReactivity

LinkML Source

Direct

name: ReceptorReactivity
from_schema: https://github.com/airr-knowledge/ak-schema
is_a: AIRRStandards
slots:
- ligand_type
- antigen_type
- antigen
- antigen_source_species
- peptide_start
- peptide_end
- mhc_class
- mhc_gene_1
- mhc_allele_1
- mhc_gene_2
- mhc_allele_2
- reactivity_method
- reactivity_readout
- reactivity_value
- reactivity_unit

Induced

name: ReceptorReactivity
from_schema: https://github.com/airr-knowledge/ak-schema
is_a: AIRRStandards
attributes:
  ligand_type:
    name: ligand_type
    annotations:
      nullable:
        tag: nullable
        value: false
    description: Classification of ligand binding to receptor
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    slot_uri: rdf:type
    alias: ligand_type
    owner: ReceptorReactivity
    domain_of:
    - ReceptorReactivity
    range: LigandTypeEnum
  antigen_type:
    name: antigen_type
    annotations:
      nullable:
        tag: nullable
        value: false
    description: The type of antigen before processing by the immune system.
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    slot_uri: rdf:type
    alias: antigen_type
    owner: ReceptorReactivity
    domain_of:
    - ReceptorReactivity
    range: AntigenTypeEnum
  antigen:
    name: antigen
    annotations:
      nullable:
        tag: nullable
        value: false
    description: The substance against which the receptor was tested. This can be
      any substance that stimulates an adaptive immune response in the host, either
      through antibody production or by T cell activation after presentation via an
      MHC molecule.
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: antigen
    owner: ReceptorReactivity
    domain_of:
    - ReceptorReactivity
    range: AntigenOntology
  antigen_source_species:
    name: antigen_source_species
    annotations:
      nullable:
        tag: nullable
        value: true
    description: The species from which the antigen was isolated
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: antigen_source_species
    owner: ReceptorReactivity
    domain_of:
    - ReceptorReactivity
    range: AntigenSourceSpeciesOntology
  peptide_start:
    name: peptide_start
    annotations:
      nullable:
        tag: nullable
        value: true
    description: Start position of the peptide within the reference protein sequence
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: peptide_start
    owner: ReceptorReactivity
    domain_of:
    - ReceptorReactivity
    range: integer
  peptide_end:
    name: peptide_end
    annotations:
      nullable:
        tag: nullable
        value: true
    description: End position of the peptide within the reference protein sequence
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: peptide_end
    owner: ReceptorReactivity
    domain_of:
    - ReceptorReactivity
    range: integer
  mhc_class:
    name: mhc_class
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: mhc_class
    owner: ReceptorReactivity
    domain_of:
    - MHCGenotype
    - ReceptorReactivity
    range: MhcClassEnum
  mhc_gene_1:
    name: mhc_gene_1
    annotations:
      nullable:
        tag: nullable
        value: true
    description: The MHC gene to which the mhc_allele_1 belongs
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: mhc_gene_1
    owner: ReceptorReactivity
    domain_of:
    - ReceptorReactivity
    range: MhcGene1Ontology
  mhc_allele_1:
    name: mhc_allele_1
    annotations:
      nullable:
        tag: nullable
        value: true
    description: Allele designation of the MHC alpha chain
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: mhc_allele_1
    owner: ReceptorReactivity
    domain_of:
    - ReceptorReactivity
    range: string
  mhc_gene_2:
    name: mhc_gene_2
    annotations:
      nullable:
        tag: nullable
        value: true
    description: The MHC gene to which the mhc_allele_2 belongs
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: mhc_gene_2
    owner: ReceptorReactivity
    domain_of:
    - ReceptorReactivity
    range: MhcGene2Ontology
  mhc_allele_2:
    name: mhc_allele_2
    annotations:
      nullable:
        tag: nullable
        value: true
    description: Allele designation of the MHC class II beta chain or the invariant
      beta2-microglobin chain
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: mhc_allele_2
    owner: ReceptorReactivity
    domain_of:
    - ReceptorReactivity
    range: string
  reactivity_method:
    name: reactivity_method
    annotations:
      nullable:
        tag: nullable
        value: false
    description: The methodology used to assess expression (assay implemented in experiment)
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: reactivity_method
    owner: ReceptorReactivity
    domain_of:
    - ReceptorReactivity
    range: ReactivityMethodEnum
  reactivity_readout:
    name: reactivity_readout
    annotations:
      nullable:
        tag: nullable
        value: false
    description: Reactivity measurement read-out
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: reactivity_readout
    owner: ReceptorReactivity
    domain_of:
    - ReceptorReactivity
    range: ReactivityReadoutEnum
  reactivity_value:
    name: reactivity_value
    annotations:
      nullable:
        tag: nullable
        value: false
    description: The absolute (processed) value of the measurement
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: reactivity_value
    owner: ReceptorReactivity
    domain_of:
    - ReceptorReactivity
    range: float
  reactivity_unit:
    name: reactivity_unit
    annotations:
      nullable:
        tag: nullable
        value: false
    description: The unit of the measurement
    from_schema: https://github.com/airr-knowledge/ak-schema
    rank: 1000
    alias: reactivity_unit
    owner: ReceptorReactivity
    domain_of:
    - ReceptorReactivity
    range: string